Neonatal eGFR

Pediatric2022Recommended

For term-born infants up to 4 weeks of age

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Calculate Neonatal

Enter the values required by this equation to estimate the result.

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For educational and clinical reference use. Interpret results in clinical context.

Formula

eGFR=0.31×heightSCr\text{eGFR} = 0.31 \times \frac{\text{height}}{\text{SCr}}

Formula constants

SymbolDescriptionValue
0.31Neonatal coefficient
HeightinputCrown–heel lengthcm
ScrS_{cr}inputSerum creatinine (IDMS-standardized)mg/dL

Required inputs

AgeHeightCreatinine

Validated age range

0 to 0.077 years

Limitations

  • Only for term-born infants
  • Limited to first 4 weeks of life
  • Requires accurate height measurement
  • Based on small neonatal studies

Clinical notes

  • Designed for term-born infants up to 4 weeks of age
  • Helps identify altered GFR in term neonates
  • Requires IDMS-standardized creatinine
  • Height should be measured in centimeters

References

  • [1]Smeets NJL, IntHout J, van der Burgh MJP, et al. Maturation of GFR in term-born neonates: An individual participant data meta-analysis. J Am Soc Nephrol. 2022;33(7):1277-1292. doi:10.1681/ASN.2021101326
  • [2]Smeets NJL, Teunissen EMM, van der Velden K, et al. Glomerular filtration rate in critically ill neonates and children: creatinine-based estimations versus iohexol-based measurements. Pediatr Nephrol. 2023;38(4):1087-1097. doi:10.1007/s00467-022-05651-w

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