CKiD U25 Extended

Pediatric2021

Extended equation for ages 1-30 years

Calculate CKiD U25 Ext

Enter the values required by this equation to estimate the result.

Enter all required values to see the result.

For educational and clinical reference use. Interpret results in clinical context.

Formula

eGFR=κ×heightSCr\text{eGFR} = \kappa \times \frac{\text{height}}{\text{SCr}}

Formula constants

SymbolDescriptionValue
κ\kappaAge- and sex-dependent coefficient (Female)
Age 1 to <12:36.1 × 1.008^(age − 12)
Age 12 to <18:36.1 × 1.023^(age − 12)
Age 18–25:41.4
Age 26–30:41.4 × 0.995^(age − 25)
κ\kappaAge- and sex-dependent coefficient (Male)
Age 1 to <12:39.0 × 1.008^(age − 12)
Age 12 to <18:39.0 × 1.045^(age − 12)
Age 18–25:50.8
Age 26–30:50.8 × 0.995^(age − 25)
HeightinputPatient heightmeters
ScrS_{cr}inputSerum creatininemg/dL

Required inputs

AgeSexHeightCreatinine

Validated age range

1 to 30 years

Limitations

  • Research-stage extension of CKiD U25
  • Limited validation beyond age 25
  • Designed for mild-to-moderate CKD populations
  • May not be appropriate for screening asymptomatic patients

Clinical notes

  • Extended CKiD equation for ages 1-30 years
  • Prevents 'jumps' when transitioning to adult equations
  • Superior estimation across extended pediatric and young adult spectrum
  • No race-based modifiers required
  • Research-stage extension of CKiD U25

References

  • [1]Pierce CB, Muñoz A, Ng DK, Warady BA, Furth SL, Schwartz GJ. Age- and sex-dependent clinical equations to estimate glomerular filtration rates in children and young adults with chronic kidney disease. Kidney Int. 2021;99(4):948-956. doi:10.1016/j.kint.2020.10.047
  • [2]Ng DK, Pierce CB. Kidney disease progression in children and young adults with pediatric CKD: Epidemiologic perspectives and clinical applications. Semin Nephrol. 2021;41(5):405-415. doi:10.1016/j.semnephrol.2021.09.002

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