FAS (Full Age Spectrum, 2016)

Adult2016

Lifespan equation covering children to adults

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Calculate FAS

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For educational and clinical reference use. Interpret results in clinical context.

Formula

For ≤40y:eGFR=107.3Scr/Q; For >40y:eGFR=107.3×(Scr/Q)−0.88×0.988age−40\text{For } \leq 40y: \text{eGFR} = \frac{107.3}{S_{cr}/Q}; \text{ For } > 40y: \text{eGFR} = 107.3 \times (S_{cr}/Q)^{-0.88} \times 0.988^{\text{age}-40}

Formula constants

SymbolDescriptionValue
107.3Base coefficient
QQMedian serum creatinine reference
Female:0.70mg/dL
Male:0.90mg/dL
−0.88Creatinine ratio exponent (age > 40 only)
0.988Age decay factor (age > 40 only)per year
ScrS_{cr}inputSerum creatininemg/dL
AgeinputPatient ageyears

Required inputs

AgeSexCreatinine

Validated age range

2 to 120 years

Limitations

  • Research-stage equation
  • Predominantly White population validation
  • Limited clinical adoption
  • Less accurate than age-specific equations

Clinical notes

  • Lifespan equation for all ages
  • Research-stage equation
  • Predominantly validated in White population
  • Simpler than age-specific equations
  • Limited clinical validation

References

  • [1]Pottel H, et al. An estimated glomerular filtration rate equation for the full age spectrum. Nephrol Dial Transplant. 2016;31(5):798-806. doi:10.1093/ndt/gfv454

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