Lund-Malmö

Adult2011

European standard equation for eGFR calculation

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Calculate Lund-Malmö

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For educational and clinical reference use. Interpret results in clinical context.

Formula

eGFR=eX−0.0158⋅age+0.438ln⁡(age) where X depends on sex and SCr threshold\text{eGFR} = e^{X - 0.0158 \cdot \text{age} + 0.438 \ln(\text{age})} \text{ where } X \text{ depends on sex and SCr threshold}

Formula constants

SymbolDescriptionValue
XPiecewise base term (sex- and SCr-dependent)
Female, pCr<150 μmol/L:2.50 + 0.0121×(150−pCr)
Female, pCr≥150 μmol/L:2.50 − 0.926×ln(pCr/150)
Male, pCr<180 μmol/L:2.56 + 0.00968×(180−pCr)
Male, pCr≥180 μmol/L:2.56 − 0.926×ln(pCr/180)
−0.0158Linear age coefficient
0.438Logarithmic age coefficient
ScrS_{cr}inputSerum creatinine (converted to μmol/L internally: ×88.4)mg/dL
AgeinputPatient ageyears

Required inputs

AgeSexCreatinine

Validated age range

18 to 120 years

Limitations

  • Developed in Swedish Caucasian population (n=850)
  • No race coefficient — not validated in non-European populations
  • Limited external validation
  • Not recommended by major US guidelines

Clinical notes

  • European standard equation
  • Developed in Swedish population
  • Good performance in European populations
  • May be less accurate in non-European populations
  • Alternative to CKD-EPI for European patients

References

  • [1]Björk J, Grubb A, Sterner G, Nyman U. Revised equations for estimating glomerular filtration rate based on the Lund-Malmö Study cohort. Scand J Clin Lab Invest. 2011;71(3):232-239. doi:10.3109/00365513.2011.557086
  • [2]Nyman U, Grubb A, Larsson A, et al. The revised Lund-Malmö GFR estimating equation outperforms MDRD and CKD-EPI across GFR, age and BMI intervals in a large Swedish population. Clin Chem Lab Med. 2014;52(6):815-824. doi:10.1515/cclm-2013-0741

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